Description

Cyclohexanecarbonyl Chloride, 5-Methyl-2-(1-Methylethyl)- (9Ci) is a specialized organic acid chloride derivative of menthol, serving as a critical building block in advanced organic synthesis. Its value lies in its high reactivity, enabling the efficient introduction of the bulky menthyl carbonyl moiety into target molecules, which is essential for modifying physical and chemical properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing chiral, lipophilic groups to modulate drug solubility and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the menthyl structure can influence stereoselective activity and environmental persistence.
• Flavor and Fragrance Chemistry: Acts as a precursor for synthesizing esters and amides with complex, long-lasting minty or woody olfactory profiles.
• Advanced Material Science: Employed in the surface modification of polymers and the creation of specialized monomers for high-performance resins.
• Catalyst and Ligand Development: Serves as a starting material for constructing chiral ligands used in asymmetric catalysis.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D for exploring new carbon-carbon and carbon-heteroatom bond-forming reactions.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 5-Methyl-2-(1-Methylethyl)- (9Ci)
CAS No.	39668-87-6
Molecular Formula	C11H19ClO
Molecular Weight	202.72 g/mol
Synonyms	L-Menthyl chloroformate; (-)-Menthyl chloroformate; (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexylcarbonyl chloride; Menthyl chloroformate; 2-Isopropyl-5-methylcyclohexanecarbonyl chloride; (1R,2S,5R)-Menthyl chloroformate; L-Menthyl chlorocarbonate
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonyl Chloride, 5-Methyl-2-(1-Methylethyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (GC/HPLC)	≥ 98.0% ee (L-Menthyl isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.