Description

4-Methylpiperazine-1-Carbonyl Chloride is a versatile and highly reactive acyl chloride derivative, primarily used as a key building block in organic synthesis. Its core value proposition lies in enabling the efficient introduction of the 4-methylpiperazine-1-carbonyl moiety, a crucial pharmacophore in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical reagent for synthesizing drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific piperazine-based structures for enhanced activity.
• Peptide Mimetics & Modifications: Facilitates the incorporation of the 4-methylpiperazine group into peptide backbones to alter pharmacokinetic properties like solubility and bioavailability.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored functional groups.
• Ligand & Catalyst Development: Employed in the creation of novel ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: A fundamental tool in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Methylpiperazine-1-Carbonyl Chloride
CAS No.	39539-66-7
Molecular Formula	C7H13ClN2O
Molecular Weight	176.65 g/mol
Synonyms	1-(Chlorocarbonyl)-4-methylpiperazine; 4-Methyl-1-piperazinecarbonyl chloride; 4-Methylpiperazine-1-carboxylic acid chloride; N-Carboxy-4-methylpiperazine chloride; 1-Piperazinecarbonyl chloride, 4-methyl-; 4-Methylpiperazino carbonyl chloride; N-(Chlorocarbonyl)-4-methylpiperazine
EINECS	Contact for details

Quality Control

Our 4-Methylpiperazine-1-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.