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2,3,4-Tri-o-Acetyl-α-D-Arabinopyranosyl Bromide CAS NO 39524-37-3
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CAS No.:39524-37-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,3,4-Tri-o-Acetyl-α-D-Arabinopyranosyl Bromide is a high-purity, protected glycosyl bromide derivative, serving as a critical glycosylation donor in synthetic organic chemistry. Its primary value lies in enabling the stereoselective construction of arabinose-containing oligosaccharides and glycoconjugates, which are essential for pharmaceutical and biochemical research. This compound is particularly vital for researchers and manufacturers in the pharmaceutical industry developing novel therapeutics, diagnostic agents, and for academic institutions engaged in carbohydrate chemistry and glycobiology studies.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, antiviral agents, and complex carbohydrate-based drugs.
- Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and neoglycoconjugates for immunological and biological studies.
- Oligosaccharide Assembly: Essential donor molecule in automated and solution-phase synthesis of arabinan oligosaccharides and related structures.
- Biochemical Probes: Enables the creation of labeled arabinose derivatives for metabolic pathway tracing and enzyme inhibition studies.
- Material Science: Potential monomer for synthesizing specialized polymers with carbohydrate backbones for biomedical applications.
- Academic & R&D: Fundamental reagent for methodological development in stereoselective glycosylation reactions within research laboratories.
Basic Information
| Product Name | 2,3,4-Tri-o-Acetyl-α-D-Arabinopyranosyl Bromide |
| CAS No. | 39524-37-3 |
| Molecular Formula | C11H15BrO7 |
| Molecular Weight | 339.14 g/mol |
| Synonyms | 2,3,4-Tri-O-acetyl-α-D-arabinopyranosyl bromide; α-D-Arabinopyranosyl bromide, 2,3,4-triacetate; 1-Bromo-2,3,4-tri-O-acetyl-α-D-arabinopyranose; Tri-O-acetyl-α-D-arabinopyranosyl bromide; Arabinose tetraacetate α-bromide; Acetylated Arabinopyranosyl Bromide; Glycosyl Bromide Donor (Arabinose) |
| EINECS | Contact for details |
Quality Control
Our 2,3,4-Tri-o-Acetyl-α-D-Arabinopyranosyl Bromide is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity suitable for advanced synthetic applications. Each lot undergoes comprehensive analytical characterization including NMR, HPLC, and optical rotation to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Optical Rotation [α]D20 | +150° to +165° (c=1 in CHCl3) |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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