Description

1,2,4-Oxadiazole-3-Carbonylchloride is a versatile and highly reactive chemical building block, primarily used as a key intermediate in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the 1,2,4-oxadiazole heterocycle, a privileged scaffold known for imparting desirable biological and material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor for synthesizing drug candidates containing the 1,2,4-oxadiazole moiety, which is associated with a wide range of pharmacological activities including anti-inflammatory, antimicrobial, and anticancer properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the oxadiazole ring contributes to stability and bioactivity.
• Material Science Research: Serves as a building block for creating advanced polymers, liquid crystals, and organic electronic materials with specific optical or electronic characteristics.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and other tools for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom chemical synthesis services catering to the needs of biotechnology and specialty chemical companies.

Basic Information

Product Name	1,2,4-Oxadiazole-3-Carbonylchloride
CAS No.	39512-69-1
Molecular Formula	C3HClN2O2
Molecular Weight	132.50 g/mol
Synonyms	3-Chlorocarbonyl-1,2,4-oxadiazole; 1,2,4-Oxadiazole-3-carbonyl chloride; 1,2,4-Oxadiazole-3-carboxylic acid chloride; Oxadiazole-3-carbonyl chloride; 3-Oxadiazolecarbonyl chloride; 3-(Chlorocarbonyl)-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Our 1,2,4-Oxadiazole-3-Carbonylchloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We employ advanced analytical techniques, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.