Description

5'-Ethylcarboxamido-2',3'-Isopropylidene Adenosine is a high-purity, protected nucleoside derivative, a key intermediate in organic synthesis and pharmaceutical research. This compound is critical for the development of novel adenosine receptor ligands and modified oligonucleotides, offering researchers precise control over molecular structure. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on nucleoside chemistry, medicinal chemistry, and prodrug development.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel adenosine analogs and potential therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop compounds targeting adenosine receptors (A1, A2A, A2B, A3).
• Prodrug Synthesis: Acts as a protected precursor for the development of nucleoside prodrugs with enhanced bioavailability or targeted delivery.
• Bioconjugation & Labeling: Utilized in the preparation of labeled nucleosides for diagnostic assays or biochemical tracking studies.
• Oligonucleotide Modification: Provides a functionalized adenosine derivative for introducing specific modifications into synthetic DNA or RNA strands.
• Chemical Biology Tool: Employed in the study of enzyme mechanisms involving adenosine, such as kinases and polymerases.

Basic Information

Item	Details
Product Name	5'-Ethylcarboxamido-2',3'-Isopropylidene Adenosine
CAS No.	39491-53-7
Molecular Formula	C16H22N6O5
Molecular Weight	378.39 g/mol
Synonyms	N6-[(1S,2R)-2-Hydroxy-1-(hydroxymethyl)-2-phenylethyl]adenosine; 2',3'-O-Isopropylidene-N6-[1(S),2(R)-2-hydroxy-1-(hydroxymethyl)-2-phenylethyl]adenosine; 5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine; Protected Adenosine Derivative; N6-(1(S),2(R)-2-Hydroxy-1-(hydroxymethyl)-2-phenylethyl)-2',3'-O-isopropylideneadenosine
EINECS	Contact for details

Quality Control

Our 5'-Ethylcarboxamido-2',3'-Isopropylidene Adenosine is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity suitable for research applications. All products undergo rigorous quality testing, including identity confirmation by spectroscopic methods (NMR, IR) and purity assessment by HPLC. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.