Description

5'-Azido-5'-Deoxyuridine is a chemically modified nucleoside analog, a key building block in medicinal chemistry and biochemical research. This compound is valued for its azido functional group, which enables efficient "click chemistry" reactions for labeling, conjugation, and the synthesis of complex biomolecular probes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for developing novel therapeutics, diagnostic agents, and advanced research tools.

Application

• Bioconjugation and Probe Synthesis: The azido group facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) for site-specific labeling of biomolecules.
• Antiviral Research: Serves as a precursor or intermediate in the development of nucleoside-based antiviral agents.
• Medicinal Chemistry: Used as a versatile scaffold for designing and synthesizing novel drug candidates targeting viral polymerases and other enzymes.
• Biochemical Tool Development: Incorporated into oligonucleotides or other molecules to create probes for studying cellular processes and enzyme mechanisms.
• Material Science: Potential use in creating functionalized surfaces or polymers for biosensor and diagnostic device applications.

Basic Information

Product Name	5'-Azido-5'-Deoxyuridine
CAS No.	39483-48-2
Molecular Formula	C9H11N5O5
Molecular Weight	269.22 g/mol
Synonyms	5'-Azido-2'-deoxy-5-uridine; 5'-Azido-5'-deoxy-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 5'-N3-dU; Azidodeoxyuridine; 5'-Azidothymidine analog; 5'-Azido-dUrd
EINECS	Contact for details

Quality Control

Our 5'-Azido-5'-Deoxyuridine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.