Description

4-Benzyloxyphenylacetyl Chloride is a versatile and highly reactive acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 4-benzyloxyphenylacetyl moiety, a key structural motif, into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, including potential enzyme inhibitors and receptor modulators.
• Peptide Mimetic Synthesis: Used to incorporate aromatic side chains and create amide bonds in the development of peptide analogs and bio-active molecules.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks.
• Material Science Research: Employed in the synthesis of monomers and functional polymers with specific optical or electronic properties.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Custom Chemical Synthesis: A fundamental reagent for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	4-Benzyloxyphenylacetyl Chloride
CAS No.	39188-62-0
Molecular Formula	C15H13ClO2
Molecular Weight	260.71 g/mol
Synonyms	2-(4-Benzyloxyphenyl)acetyl Chloride; p-Benzyloxyphenylacetyl Chloride; 4-(Benzyloxy)benzeneacetyl Chloride; (4-Benzyloxyphenyl)acetyl Chloride; 2-(4-(Phenylmethoxy)phenyl)acetyl Chloride; α-Chloro-4-benzyloxyacetophenone; 4-Benzyloxy-α-chloroacetophenone
EINECS	Contact for details

Quality Control

Our 4-Benzyloxyphenylacetyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.