Description

2-Thiopheneacetyl Chloride is a versatile and highly reactive organosulfur building block, primarily used as an acylating agent in organic synthesis. Its value lies in its ability to efficiently introduce the 2-thiopheneacetyl moiety, a key structural motif in the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates containing thiophene rings.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the thiophene unit imparts specific biological activity.
• Polymer & Material Science: Serves as a monomer or modifying agent for creating polymers with unique electronic or optical properties.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Organic Synthesis Building Block: A key reagent for peptide coupling and the acylation of amines, alcohols, and other nucleophiles in complex molecule assembly.
• Research & Development: Fundamental reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Thiopheneacetyl Chloride
CAS No.	39098-97-0
Molecular Formula	C6H5ClOS
Molecular Weight	160.62 g/mol
Synonyms	2-(Thiophen-2-yl)acetyl chloride; (Thiophen-2-yl)acetyl chloride; 2-Thienylacetyl chloride; α-Thiopheneacetyl chloride; 2-Thiopheneacetic acid chloride; Thiophene-2-acetyl chloride; 2-Thiopheneglyoxylic acid chloride; TAC
EINECS	Contact for details

Quality Control

Our 2-Thiopheneacetyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.