Description

3-(4-Fluorophenyl)-2-Propenoylhloride is a reactive organic intermediate featuring a fluorinated aromatic ring and an acid chloride functional group. This compound is valued for its role as a key building block in the synthesis of more complex molecules, enabling the introduction of the 4-fluorocinnamoyl moiety. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the bioactivity of the fluorophenyl group.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials requiring specific fluorinated aromatic structures.
• Polymer Modification: Employed to introduce photoreactive or cross-linking sites into polymer chains for specialty coatings and resins.
• Chemical Research & Development: A versatile reagent for academic and industrial research in organic synthesis and methodology development.
• Peptide Mimetics & Bioconjugation: The acid chloride group is reactive towards amines, making it useful for creating peptide analogs or labeling biomolecules.

Basic Information

Product Name	3-(4-Fluorophenyl)-2-Propenoylhloride
CAS No.	39098-89-0
Molecular Formula	C9H6ClFO
Molecular Weight	184.60 g/mol
Synonyms	4-Fluorocinnamoyl Chloride; (E)-3-(4-Fluorophenyl)acryloyl Chloride; trans-4-Fluorocinnamoyl Chloride; 3-(4-Fluorophenyl)propenoyl Chloride; (2E)-3-(4-Fluorophenyl)prop-2-enoyl Chloride; 4-Fluorocinnamein Chloride; p-Fluorocinnamoyl Chloride
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-2-Propenoylhloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.