tert-Butyl 2-Chloro-2-Oxoacetate CAS NO 39061-59-1

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CAS No.:39061-59-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl 2-chloro-2-oxoacetate is a versatile and reactive organic building block, primarily used as an acylating agent and a key intermediate in the synthesis of complex molecules. Its value lies in the tert-butyl ester group, which offers steric protection and can be selectively cleaved under mild acidic conditions, making it a strategic reagent in multi-step synthetic routes. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing active ingredients and advanced materials.

Application

Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing glyoxylate or α-keto acid moieties.
Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its reactive chloro and keto groups facilitate further chemical modifications.
Peptide Chemistry & Biochemistry: Serves as a reagent for modifying amino acids or synthesizing peptide mimetics and enzyme inhibitors.
Organic Synthesis Building Block: Employed in Friedel-Crafts acylation, Grignard reactions, and nucleophilic substitution reactions to construct complex organic frameworks.
Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers and functional materials.
Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information


Product Name	tert-Butyl 2-Chloro-2-Oxoacetate
CAS No.	39061-59-1
Molecular Formula	C6H9ClO3
Molecular Weight	164.59 g/mol
Synonyms	tert-Butyl Chloroglyoxylate; 2-Chloro-2-oxoacetic acid tert-butyl ester; Chlorooxoacetic acid tert-butyl ester; tert-Butyl Chlorooxoacetate; tert-Butyl α-Chloro-α-oxoacetate; Glyoxylic acid, 2-chloro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 2-chloro-2-oxoacetate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-chloro-2-oxoacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and relevant impurities is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong acids and incompatible materials.