Description

(Z)-Guggulsterone CAS NO 39025-23-5 is a specific stereoisomer of the bioactive phytosterol found in the resin of the Commiphora wightii tree. This compound is valued for its role as a key reference standard and active ingredient in research and development, particularly for its interaction with nuclear receptors. It is primarily sought by manufacturers and researchers in the pharmaceutical, nutraceutical, and cosmetic industries for applications in metabolic health, inflammation, and skincare formulations.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and research in drug development.
• Nutraceutical Formulations: Incorporated into dietary supplements targeting cholesterol management and metabolic support.
• Cosmetic Actives: Serves as a functional ingredient in anti-aging and anti-acne skincare products for its purported regulatory effects on skin lipids.
• Biochemical Research: Employed in vitro and in vivo studies to investigate Farnesoid X Receptor (FXR) antagonism and related metabolic pathways.
• Traditional Medicine Modernization: Used in the standardization of herbal extracts derived from guggul resin for consistent potency.

Basic Information

Product Name	(Z)-Guggulsterone
CAS No.	39025-23-5
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	(Z)-Guggulsterone; cis-Guggulsterone; (17Z)-Pregna-4,17(20)-diene-3,16-dione; NSC 69850; Guggulsterone Z isomer; Commiphora mukul extract constituent
EINECS	Contact for details

Quality Control

Our (Z)-Guggulsterone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.