Description

Suberohydroxamic Acid CAS NO 38937-66-5 is a potent and selective hydroxamic acid derivative that functions as a critical inhibitor of metalloenzymes, particularly histone deacetylases (HDACs). Its primary value lies in its role as a key research chemical and pharmaceutical intermediate for developing novel therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors focused on oncology, neurology, and epigenetic research.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel histone deacetylase (HDAC) inhibitor drugs for cancer therapy.
• Biochemical Research: Used as a selective enzyme inhibitor in academic and industrial laboratories to study HDAC activity and epigenetic mechanisms.
• Drug Discovery & Development: Employed in high-throughput screening and lead optimization processes for new therapeutic candidates targeting various diseases.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Life Science Reagent: Utilized in cell-based assays and in-vitro studies to investigate cellular differentiation, apoptosis, and gene expression.

Basic Information

Product Name	Suberohydroxamic Acid
CAS No.	38937-66-5
Molecular Formula	C8H17NO3
Molecular Weight	175.23 g/mol
Synonyms	Suberic Hydroxamic Acid; Octanediohydroxamic Acid; 1,7-Dicarboxy-6-hydroxyaminohexane; SAHA Impurity; Vorinostat Related Compound; HDAC Inhibitor; N-Hydroxyoctanediamide; 8-Hydroxyamino-8-oxooctanoic Acid
EINECS	Contact for details

Quality Control

Our Suberohydroxamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for identification, and stringent controls for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere when appropriate. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.