Description

Guanosine Pentaphosphate is a high-purity nucleotide derivative, a pentaphosphate ester of guanosine. This compound is a critical biochemical reagent and building block for advanced research and synthesis. It is primarily utilized in life science research, pharmaceutical development, and as a precursor for specialized nucleotide analogs. The product is supplied as Guanosine Pentaphosphate CAS NO 38918-96-6, meeting stringent quality standards for sensitive applications.

Application

• Biochemical Research: Used as a substrate or cofactor in enzymatic studies, particularly those involving kinases, polymerases, and other nucleotide-dependent enzymes.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor for novel antiviral or anticancer nucleotide analog drugs.
• Diagnostic Reagent Manufacturing: Employed in the production of high-sensitivity assay kits for cellular energy metabolism (ATP/ADP/AMP) analysis.
• Cell Signaling Studies: Applied in research focused on purinergic signaling pathways and intracellular second messenger systems.
• Enzyme Catalysis Studies: Acts as a high-energy phosphate donor in mechanistic studies of ATP-dependent enzymes.
• Reference Standard: Used as an analytical standard in HPLC or LC-MS for quality control and method validation in pharmaceutical and research laboratories.

Basic Information

Product Name	Guanosine Pentaphosphate
CAS No.	38918-96-6
Molecular Formula	C10H17N5O19P5
Molecular Weight	677.13 g/mol
Synonyms	Guanosine-5'-pentaphosphate; pppppG; 5'-Guanosine pentaphosphate; Guanosine 5'-(pentahydrogen pentaphosphate); Gppppp; Guanosine-5'-pentakisphosphate; P1,P5-Di(guanosin-5'-yl) pentaphosphate (isomeric form)
EINECS	Contact for details

Quality Control

Our Guanosine Pentaphosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 10 ppm
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.