Description

8-Azanebularine is a purine nucleoside analog with significant research and development applications. This compound matters as a versatile building block and a key intermediate in the synthesis of modified nucleosides and nucleotides, which are crucial for pharmaceutical and biochemical research. It is primarily needed by research institutions and pharmaceutical companies engaged in antiviral drug discovery, oncology research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Antiviral Agent Development: Serves as a core structure for developing compounds that target viral polymerases and replication mechanisms.
• Oncology Research: Investigated for its potential to interfere with DNA/RNA synthesis in rapidly dividing cancer cells.
• Chemical Biology Tool: Employed in the study of nucleic acid structure, function, and protein-nucleic acid interactions.
• Academic & Industrial R&D: A fundamental building block for medicinal chemistry programs exploring new therapeutic modalities.

Basic Information

Product Name	8-Azanebularine
CAS No.	38874-46-3
Molecular Formula	C9H11N5O4
Molecular Weight	253.22 g/mol
Synonyms	8-Aza-7-deazaguanosine; 8-Aza-7-deaza-Guanosine; 8-Aza-7-deazaguanosine riboside; 8-Aza-7-deazaguanine riboside; 4-Amino-5-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 8-Aza-7-deazaguanine nucleoside; Pyrrolo[2,3-d]pyrimidine ribonucleoside analog
EINECS	Contact for details

Quality Control

Our 8-Azanebularine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.