Description

3-(β-D-Ribofuranosyl)-7-(Dimethylamino)-3H-1,2,3-Triazolo[4,5-D]Pyrimidine is a specialized nucleoside analog with a unique triazolopyrimidine structure, offering significant value as a key building block in advanced biochemical research and pharmaceutical development. Its primary importance lies in its role as a precursor or intermediate for novel antiviral and anticancer agents, particularly in the synthesis of modified nucleosides and nucleotides. This high-purity compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving nucleoside-metabolizing enzymes.
• Probe Development: Serves as a core structure for developing fluorescent or radioactive probes to study nucleic acid interactions and cellular processes.
• Antiviral Agent Synthesis: A key precursor in the research and development of potential therapeutic agents targeting viral polymerases.
• Nucleic Acid Chemistry: Employed in the study of modified nucleosides and their incorporation into oligonucleotides for stability and functional studies.
• Library Synthesis: Used in combinatorial chemistry and medicinal chemistry programs to create diverse libraries of bioactive molecules for screening.

Basic Information

Product Name	3-(β-D-Ribofuranosyl)-7-(Dimethylamino)-3H-1,2,3-Triazolo[4,5-D]Pyrimidine
CAS No.	38874-44-1
Molecular Formula	C11H16N6O4
Molecular Weight	296.29 g/mol
Synonyms	7-(Dimethylamino)-3-(β-D-ribofuranosyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine; 3-β-D-Ribofuranosyl-7-(dimethylamino)-3H-v-triazolo[4,5-d]pyrimidine; 7-Dimethylamino-3-β-D-ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidine; 7-(N,N-Dimethylamino)-3-(β-D-ribofuranosyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine; 3H-1,2,3-Triazolo[4,5-d]pyrimidine, 7-(dimethylamino)-3-β-D-ribofuranosyl-; Modified Nucleoside Intermediate; Triazolopyrimidine Nucleoside
EINECS	Contact for details

Quality Control

Our production of 3-(β-D-Ribofuranosyl)-7-(Dimethylamino)-3H-1,2,3-Triazolo[4,5-D]Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.