Description

Cyclohexanecarbonyl Chloride, 1,3-Dimethyl-, trans- (9Ci) is a specialized organic acid chloride derivative of a substituted cyclohexane carboxylic acid. This compound serves as a versatile and critical building block in advanced organic synthesis, enabling the introduction of the sterically defined 1,3-dimethylcyclohexanecarbonyl moiety. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a rigid, substituted cyclohexane backbone.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where specific stereochemistry influences bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Employed in the synthesis of specialty monomers and polymers to impart specific thermal and mechanical properties.
• Material Science Research: Used in the development of liquid crystals, organic semiconductors, and other advanced functional materials.
• Peptide Mimetics: Facilitates the incorporation of constrained, non-natural amino acid analogs into peptide chains for drug discovery.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 1,3-Dimethyl-, trans- (9Ci)
CAS No.	38864-03-8
Molecular Formula	C9H15ClO
Molecular Weight	174.67 g/mol
Synonyms	trans-1,3-Dimethylcyclohexanecarbonyl Chloride; (1R,3S)-1,3-Dimethylcyclohexanecarbonyl Chloride; (1S,3R)-1,3-Dimethylcyclohexanecarbonyl Chloride; 1,3-Dimethylcyclohexanecarboxylic Acid Chloride, trans-; Cyclohexanecarboxylic Acid, 1,3-Dimethyl-, Chloride, trans-; 38864-03-8; trans-1,3-Dimethylcyclohexanoyl Chloride
EINECS	Contact for details

Quality Control

Our trans-1,3-Dimethylcyclohexanecarbonyl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including GC, HPLC, and NMR to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring material that meets high-purity standards for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain purity and prevent hydrolysis.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (trans-)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.