Description

Indoramin Hydrochloride is a selective α-1 adrenergic receptor antagonist of significant pharmaceutical importance. This compound is valued for its specific pharmacological activity, making it a key intermediate and active pharmaceutical ingredient (API) in therapeutic development. It is primarily required by pharmaceutical manufacturers and research institutions engaged in cardiovascular drug discovery and production.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of antihypertensive medications.
• Research & Development: Critical reference standard and biochemical tool in cardiovascular and autonomic nervous system research.
• Generic Drug Manufacturing: Sourcing for the production of generic versions of α-blocker therapies.
• Clinical Trial Material: Used as a bulk drug substance in the preparation of materials for clinical studies.
• Analytical Standard: Serves as a high-purity standard for quality control (QC) and analytical method development (e.g., HPLC, dissolution testing).

Basic Information

Product Name	Indoramin Hydrochloride
CAS No.	38821-52-2
Molecular Formula	C22H25ClN2O3 • HCl
Molecular Weight	433.36 g/mol (as hydrochloride salt)
Synonyms	Indoramin HCl; 1-(4-Amidinophenoxy)-3-[(1-methyl-2-indolyl)ethylamino]-2-propanol Hydrochloride; 3-[2-(1H-Indol-3-yl)ethylamino]-1-(4-amidinophenoxy)-2-propanol Hydrochloride; Wy-21901; Baratol (brand name); Indoramini Hydrochloridum; N-[2-(1H-Indol-3-yl)ethyl]-N'-[2-hydroxy-3-(4-hydroxyphenoxy)propyl]piperazine Hydrochloride
EINECS	Contact for details

Quality Control

Our Indoramin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.