Description

1-Chloro-4-[(2-Isothiocyanatoethyl)Thio]Benzene is a specialized organic compound featuring both a reactive isothiocyanate group and a chlorinated aromatic core. This unique bifunctional structure makes it a valuable chemical intermediate for synthesizing more complex molecules, particularly in advanced research and development. It is primarily utilized by the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting specific biological pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides.
• Bioconjugation Reagent: The isothiocyanate group enables covalent bonding to amine groups, useful in labeling proteins, antibodies, and other biomolecules for diagnostic or research purposes.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology Probes: Employed in the design of activity-based probes for studying enzyme function and cellular processes.
• Ligand Synthesis: Useful for creating complex ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	1-Chloro-4-[(2-Isothiocyanatoethyl)Thio]Benzene
CAS No.	38752-40-8
Molecular Formula	C9H8ClNS2
Molecular Weight	229.75 g/mol
Synonyms	4-Chlorophenyl 2-isothiocyanatoethyl sulfide; NSC 403016; 1-Chloro-4-[(2-isothiocyanatoethyl)sulfanyl]benzene; p-Chlorophenyl 2-isothiocyanatoethyl sulfide; 2-[(4-Chlorophenyl)thio]ethyl isothiocyanate; Benzene, 1-chloro-4-[(2-isothiocyanatoethyl)thio]-; (2-Isothiocyanatoethyl)(4-chlorophenyl) sulfide
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-[(2-Isothiocyanatoethyl)Thio]Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC and NMR to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.