Description

5-β-Cholanic Acid-3-Alpha, 6-α-Diol n-(Carboxymethyl)-Amide Sodium Salt is a high-purity, chemically modified bile acid derivative with significant value in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or active pharmaceutical ingredient (API) for developing novel therapeutic agents targeting metabolic and hepatic pathways. It is primarily required by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in the synthesis of steroidal drugs, receptor modulators, and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal therapeutics and bile acid analogs.
• Active Pharmaceutical Ingredient (API): Potential use as a core component in formulations targeting liver and metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in studies of bile acid transporters (e.g., ASBT, NTCP) and nuclear receptors (e.g., FXR, TGR5).
• Diagnostic Agent Development: Serves as a precursor for developing contrast agents or radiopharmaceuticals for hepatobiliary imaging.
• Chemical Synthesis: Utilized in organic synthesis for introducing specific steroidal frameworks with carboxylate and amide functionalities.
• Life Science Reagents: Component in cell culture media or biochemical assay kits studying cholesterol metabolism and bile acid signaling.

Basic Information

Product Name	5-β-Cholanic Acid-3-Alpha, 6-α-Diol n-(Carboxymethyl)-Amide Sodium Salt
CAS No.	38411-84-6
Molecular Formula	C26H42NNaO5
Molecular Weight	471.61 g/mol
Synonyms	3α,6α-Dihydroxy-5β-cholan-24-oic Acid N-(Carboxymethyl)amide Sodium Salt; Sodium 3α,6α-Dihydroxy-5β-cholan-24-oyl-glycinate; Glyco-3α,6α-dihydroxy-5β-cholan-24-oyltaurate Sodium Salt (common naming); N-(Carboxymethyl)-3α,6α-dihydroxy-5β-cholan-24-amide Sodium Salt; Tauro-3α,6α-dihydroxy-5β-cholanoic Acid Sodium Salt (analogous naming); 5β-Cholanic Acid-3α,6α-diol N-(Carboxymethyl)amide Sodium Salt; 38411-84-6 (CAS Index Name base); Cholylglycine Dihydroxy Analog Sodium Salt
EINECS	Contact for details

Quality Control

Our 5-β-Cholanic Acid-3-Alpha, 6-α-Diol n-(Carboxymethyl)-Amide Sodium Salt is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent controls for residual solvents and heavy metals to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.