Description

(17S,22R)-5,6β-Epoxy-14,17,20,22-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is a highly functionalized ergostane-type steroidal lactone, representing a key advanced intermediate in the synthesis of complex bioactive molecules. Its intricate polycyclic structure with multiple chiral centers makes it a valuable scaffold for pharmaceutical research and development. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas such as oncology and metabolic disease.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel steroidal drugs and investigational compounds.
• Biochemical Research: Used as a reference standard or probe in studies of sterol biosynthesis and metabolic pathways.
• Medicinal Chemistry: Provides a complex, chiral core structure for structure-activity relationship (SAR) studies and lead optimization.
• Academic Research: Employed in universities and research institutes for synthetic methodology development and natural product synthesis.
• Process Development: Utilized in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(17S,22R)-5,6β-Epoxy-14,17,20,22-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone
CAS No.	38254-15-8
Molecular Formula	C₂₈H₃₈O₈
Molecular Weight	502.60 g/mol
Synonyms	5,6β-Epoxy-14,17,20,22-tetrahydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid δ-lactone; (17S,22R)-5,6β-Epoxy-14,17,20,22-tetrahydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid δ-lactone; 5,6β-Epoxyergosta-2,24-dien-26-oic acid δ-lactone derivative; Steroidal epoxy lactone; Ergostane lactone intermediate
EINECS	Contact for details

Quality Control

Our (17S,22R)-5,6β-Epoxy-14,17,20,22-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.