Description

2-Chloro-4α,5α-Dimethyl-1,3,2-Dioxaphospholane is a specialized organophosphorus compound, specifically a cyclic chlorophosphite ester, serving as a critical intermediate in advanced chemical synthesis. Its primary value lies in its high reactivity as a versatile phosphorylating and coupling agent, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional polymers. The CAS number for this product is 38206-22-3.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel nucleotide analogs, prodrugs, and other bioactive molecules with potential therapeutic applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific phosphorus-containing functional groups.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers, including flame retardants and materials with tailored surface properties.
• Ligand & Catalyst Preparation: Serves as a precursor for creating chiral phosphite and phosphoramidite ligands used in asymmetric catalysis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new phosphorylation reactions and developing novel synthetic methodologies.
• Material Science: Utilized in surface modification and the creation of advanced functional materials with specific electronic or optical characteristics.

Basic Information

Product Name	2-Chloro-4α,5α-Dimethyl-1,3,2-Dioxaphospholane
CAS No.	38206-22-3
Molecular Formula	C₅H₁₀ClO₂P
Molecular Weight	168.56 g/mol
Synonyms	2-Chloro-4,5-dimethyl-1,3,2-dioxaphospholane; 4,5-Dimethyl-2-chloro-1,3,2-dioxaphospholane; Chloro(4,5-dimethyl-1,3,2-dioxaphospholane); 1,3,2-Dioxaphospholane, 2-chloro-4,5-dimethyl-; (4R,5R)-2-Chloro-4,5-dimethyl-1,3,2-dioxaphospholane (for chiral forms); Cyclic chlorophosphite ester; DMCP
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4α,5α-Dimethyl-1,3,2-Dioxaphospholane is manufactured and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.