Description

4,5-Dihydro-3-[(trimethylsilyl)oxy]-3-[(trimethylsilyl)oxymethyl]-2(3H)-furanone is a specialized organosilicon-protected lactone derivative that serves as a versatile synthetic intermediate. Its core value proposition lies in its dual silyl ether protection, which provides enhanced stability and reactivity control for advanced organic synthesis. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its protected functional groups for selective reactions.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring precise stereochemistry.
• Academic & Industrial Research: Valuable reagent in methodological development and total synthesis projects within organic chemistry laboratories.
• Material Science: Potential monomer or modifier in the development of specialized silicon-containing polymers and coatings.

Basic Information

Product Name	4,5-Dihydro-3-[(trimethylsilyl)oxy]-3-[(trimethylsilyl)oxymethyl]-2(3H)-furanone
CAS No.	38166-06-2
Molecular Formula	C12H26O4Si2
Molecular Weight	290.51 g/mol
Synonyms	3-[(Trimethylsilyl)oxy]-3-[(trimethylsilyl)oxymethyl]dihydro-2(3H)-furanone; 3,3-Bis(trimethylsiloxy)tetrahydrofuran-2-one; 3-Hydroxy-3-(hydroxymethyl)dihydro-2(3H)-furanone bis(trimethylsilyl) ether; TMS-protected tetronic acid derivative; Bis(trimethylsilyl) ether of 3-hydroxy-3-(hydroxymethyl)dihydrofuran-2(3H)-one
EINECS	Contact for details

Quality Control

Our production of 4,5-Dihydro-3-[(trimethylsilyl)oxy]-3-[(trimethylsilyl)oxymethyl]-2(3H)-furanone adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. All materials undergo rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can compromise product integrity. For long-term storage, consider using desiccants or storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.