Description

2-Methyl-2,3-Bis(Trimethylsilyloxy)Propionic Acid Trimethylsilyl Ester is a specialized organosilicon compound that serves as a versatile silylating agent and protected intermediate in advanced organic synthesis. Its value lies in its ability to introduce trimethylsilyl (TMS) protecting groups for hydroxyl and carboxyl functionalities, enhancing the solubility and stability of sensitive molecules during complex reaction sequences. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex APIs, natural products, and novel silicon-containing materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) requiring hydroxyl and carboxyl group protection.
• Fine Chemical Synthesis: Used as a silylating agent in multi-step organic synthesis to protect sensitive functional groups from unwanted side reactions.
• Silicon Chemistry Research: A valuable precursor for developing novel organosilicon compounds and materials with tailored properties.
• Natural Product Derivatization: Facilitates the modification and purification of complex natural products by protecting polar functional groups.
• Polymer Science: Employed in the synthesis of specialized silicone-based polymers and hybrid organic-inorganic materials.
• Analytical Chemistry: Can be used to derivatize compounds for Gas Chromatography (GC) or Mass Spectrometry (MS) analysis to improve volatility and detection.

Basic Information

Item	Details
Product Name	2-Methyl-2,3-Bis(Trimethylsilyloxy)Propionic Acid Trimethylsilyl Ester
CAS No.	38166-00-6
Molecular Formula	C15H36O5Si3
Molecular Weight	380.70 g/mol
Synonyms	2-Methyl-2,3-bis[(trimethylsilyl)oxy]propanoic acid trimethylsilyl ester; 2-Methyl-2,3-bis(trimethylsiloxy)propionic acid trimethylsilyl ester; 2-Methyl-2,3-bis(trimethylsilyloxy)propanoic acid trimethylsilyl ester; 2,3-Bis-O-(trimethylsilyl)-2-methyl-3-hydroxypropionic acid trimethylsilyl ester; TMS ester of 2-methyl-2,3-bis(trimethylsilyloxy)propionic acid; Propanoic acid, 2-methyl-2,3-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-2,3-Bis(Trimethylsilyloxy)Propionic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC or HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.