Description

Arabino-Hexaric Acid, 2-Deoxy-3,4,5-Tris-o-(Trimethylsilyl)-, Bis(Trimethylsilyl) Ester is a highly functionalized, fully silylated derivative of a deoxy hexaric acid, designed for advanced synthetic and analytical chemistry. This compound is valued for its role as a key protected intermediate and a reference standard in carbohydrate and nucleoside chemistry research. It is essential for pharmaceutical R&D, academic laboratories, and fine chemical synthesis focused on developing novel therapeutics, diagnostics, and complex biomolecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial protected building block in the synthesis of nucleoside analogs, antiviral agents, and other bioactive carbohydrate derivatives.
• Glycochemistry Research: Used as a standardized intermediate for studying glycosylation reactions, carbohydrate transformations, and enzyme inhibition mechanisms.
• Analytical Reference Standard: Employed in HPLC, GC-MS, and NMR as a high-purity calibrant or internal standard for method development and quality control in analytical laboratories.
• Process Chemistry Development: Acts as a starting material or intermediate in scaling up synthetic routes for complex organic molecules in fine chemical and API manufacturing.
• Protecting Group Strategy: The trimethylsilyl (TMS) groups provide robust protection for hydroxyl functionalities, enabling selective reactions in multi-step syntheses.
• Bioconjugation & Probe Synthesis: Utilized in the development of labeled probes, linkers, and conjugates for biochemical and diagnostic applications.

Basic Information

Product Name	Arabino-Hexaric Acid, 2-Deoxy-3,4,5-Tris-o-(Trimethylsilyl)-, Bis(Trimethylsilyl) Ester
CAS No.	38165-98-9
Molecular Formula	C24H56O6Si5
Molecular Weight	609.2 g/mol
Synonyms	2-Deoxy-3,4,5-tris-O-(trimethylsilyl)-arabino-hexaric acid bis(trimethylsilyl) ester; 2-Deoxy-3,4,5-tris-O-TMS-arabino-hexaric acid bis-TMS ester; Fully silylated 2-deoxyarabino-hexaric acid; Hexaric acid, 2-deoxy-3,4,5-tris-O-(trimethylsilyl)-, bis(trimethylsilyl) ester; TMS-protected 2-deoxy hexaric acid derivative; Carbohydrate TMS derivative; CAS 38165-98-9
EINECS	Contact for details

Quality Control

Every batch of Arabino-Hexaric Acid, 2-Deoxy-3,4,5-Tris-o-(Trimethylsilyl)-, Bis(Trimethylsilyl) Ester is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions, such as in a glovebox or under a dry inert atmosphere (argon/nitrogen), to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.