Description

3β-Hydroxy-5,6β-Cyclopropano-5β-Cholestane CAS NO 38037-44-4 is a high-purity steroidal derivative characterized by a unique cyclopropane ring fused to the sterol B-ring structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile research chemical for the synthesis of novel bioactive molecules. It is essential for R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop new therapeutic agents or study sterol metabolism and signaling pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of cholesterol metabolism, membrane biology, and hormone receptor interactions.
• Organic Synthesis: A versatile chiral starting material for constructing complex natural products and steroidal architectures with modified biological activity.
• Academic & Industrial R&D: Fundamental material for investigating structure-activity relationships (SAR) in medicinal chemistry programs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high-purity sterol derivatives.

Basic Information

Product Name	3β-Hydroxy-5,6β-Cyclopropano-5β-Cholestane
CAS No.	38037-44-4
Molecular Formula	C30H52O
Molecular Weight	428.74 g/mol
Synonyms	3β-Hydroxy-5,6β-cyclopropano-5β-cholestane; 5β-Cholestane-3β-ol, 5,6β-cyclopropano-; (3β,5β,6β)-5,6-Cyclopropanocholestan-3-ol; 5,6β-Cyclopropano-5β-cholestan-3β-ol; Cyclopropanocholestanol derivative; Sterol cyclopropane derivative
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.