Description

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethyl-3-Oxo-1-Cyclohexenyl)Nona-2,4,6,8-Tetraenoic Acid is a high-purity synthetic retinoid derivative, a key intermediate in the production of advanced pharmaceutical compounds. Its precise stereochemistry and defined structure make it an essential building block for research and development in targeted therapies. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in the synthesis of vitamin A analogs and novel retinoid-based drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel retinoid drugs and vitamin A analogs for dermatology and oncology applications.
• Biochemical Research: Used as a reference standard and active agent in studies of retinoid receptor (RAR/RXR) signaling pathways and cellular differentiation.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules with specific geometric isomerism in advanced organic synthesis.
• Cosmetic Ingredient Development: Employed in R&D for next-generation anti-aging and skin-renewal cosmetic actives, though final formulations require strict regulatory compliance.

Basic Information

Product Name	(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethyl-3-Oxo-1-Cyclohexenyl)Nona-2,4,6,8-Tetraenoic Acid
CAS No.	38030-57-8
Molecular Formula	C20H28O3
Molecular Weight	316.44 g/mol
Synonyms	9-cis-Retinoic Acid; Isotretinoin Impurity F; Alitretinoin Related Compound; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic Acid; 9Z-Retinoic Acid; Panretin Impurity; 9-cis-Retinoid Acid; LGD1069 Related Compound
EINECS	Contact for details

Quality Control

Our (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethyl-3-Oxo-1-Cyclohexenyl)Nona-2,4,6,8-Tetraenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and isomer profile confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Isomer Profile (HPLC)	Report and conforms to customer requirement
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.