Description

Androst-5-En-17-One, 7-(Acetyloxy)-3-Hydroxy-, (3Beta,7Alpha)- (9Ci) is a high-purity steroid derivative, specifically a 7α-acetoxy-3β-hydroxyandrost-5-en-17-one, serving as a critical advanced intermediate in pharmaceutical synthesis. Its precise stereochemistry and functional groups make it a valuable building block for developing novel therapeutic agents targeting hormonal pathways. This compound is essential for research and development laboratories, custom synthesis houses, and pharmaceutical manufacturers focused on endocrinology and metabolic disease treatments.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) for new drug candidates targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in enzymatic studies to investigate steroid metabolism and biosynthesis pathways.
• Custom Synthesis: A starting material for the contract manufacturing of specialized steroid derivatives for clinical trials and niche applications.

Basic Information

Product Name	Androst-5-En-17-One, 7-(Acetyloxy)-3-Hydroxy-, (3Beta,7Alpha)- (9Ci)
CAS No.	37976-97-9
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	7α-Acetoxy-3β-hydroxyandrost-5-en-17-one; 3β,7α-Dihydroxyandrost-5-en-17-one 7-acetate; (3β,7α)-7-(Acetyloxy)-3-hydroxyandrost-5-en-17-one; 7α-Acetoxy-DHEA; 7α-Acetoxy-Dehydroepiandrosterone; 37976-97-9; Androst-5-en-17-one, 7-(acetyloxy)-3-hydroxy-, (3β,7α)-
EINECS	Contact for details

Quality Control

Every batch of Androst-5-En-17-One, 7-(Acetyloxy)-3-Hydroxy-, (3Beta,7Alpha)- (9Ci) is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets specifications suitable for research and advanced synthesis. Certificates of Analysis (COA) detailing HPLC purity, chiral purity, and related substance profiles are provided with each shipment. We support development of custom grades to meet specific project requirements, including those aligned with cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (7α-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.