Description

(20R)-5α-Cholesta-9(11),24-Diene-3β,6α,20-Triol is a high-purity, multi-hydroxylated sterol derivative of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical intermediate and reference standard for the synthesis and study of complex steroid hormones and their metabolites. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality building blocks for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and precursor in metabolic pathway studies, enzyme inhibition assays, and receptor binding studies.
• Steroid Chemistry: Serves as a versatile starting material for the preparation of other hydroxylated sterols and bile acid analogs.
• Drug Discovery: Employed in high-throughput screening (HTS) and medicinal chemistry programs targeting nuclear receptors and metabolic enzymes.
• Analytical Standard: Provides a certified reference material for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	(20R)-5α-Cholesta-9(11),24-Diene-3β,6α,20-Triol
CAS No.	37926-46-8
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	(20R)-5α-Cholesta-9(11),24-diene-3β,6α,20-triol; 3β,6α,20-Trihydroxy-5α-cholesta-9(11),24-diene; 5α-Cholesta-9(11),24-diene-3β,6α,20(R)-triol; 20(R)-Hydroxycholesterol derivative; 9(11)-Dehydro-20(R)-hydroxycholesterol; Sterol triol intermediate
EINECS	Contact for details

Quality Control

Our (20R)-5α-Cholesta-9(11),24-Diene-3β,6α,20-Triol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.