Description

Bicyclo[5.1.0]Octa-2,4-Diene-8-Carbonyl Chloride (7Ci,9Ci) is a highly reactive and versatile strained bicyclic building block, specifically engineered for advanced synthetic chemistry. Its unique fused ring system and acid chloride functionality make it an indispensable precursor for constructing complex molecular architectures with high precision. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those requiring strained, three-dimensional core structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its unique scaffold can impart specific biological activity.
• Material Science Research: Serves as a precursor for creating specialized polymers or ligands with tailored electronic or steric properties.
• Cross-Coupling Reactions: The acid chloride group is readily converted to other functionalities (amides, esters, ketones) for use in palladium-catalyzed and other metal-mediated couplings.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chiral or sterically hindered ligands for asymmetric catalysis.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, exploring new cycloaddition and ring-opening reactions.

Basic Information

Product Name	Bicyclo[5.1.0]Octa-2,4-Diene-8-Carbonyl Chloride (7Ci,9Ci)
CAS No.	37907-01-0
Molecular Formula	C9H7ClO
Molecular Weight	166.60 g/mol
Synonyms	8-Bicyclo[5.1.0]octa-2,4-dien-8-ylcarbonyl chloride; Bicyclo[5.1.0]octa-2,4-diene-8-carbonyl chloride; (1R,6S,7S)-Bicyclo[5.1.0]octa-2,4-diene-8-carbonyl chloride; (1S,6R,7R)-Bicyclo[5.1.0]octa-2,4-diene-8-carbonyl chloride; 7-Carbabicyclo[5.1.0]octa-2,4-diene-8-carbonyl chloride; 37907-01-0; Bicyclo[5.1.0]octa-2,4-dien-8-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[5.1.0]Octa-2,4-Diene-8-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at recommended temperatures between 2°C and 8°C (refrigerated) or as specified on the label. This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.