Description

Benzeneacetyl Chloride, 4-Hydroxy- CAS NO 37859-23-7 is a key aromatic acid chloride derivative, serving as a versatile and reactive building block in advanced organic synthesis. Its value lies in its ability to introduce the 4-hydroxybenzoyl moiety, a crucial structural element in various high-value compounds, under controlled conditions. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phenolic ester or amide functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the hydroxybenzoyl group enhances biological activity.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the creation of specialty polymers and liquid crystal materials for electronic displays.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex organic dyes and pigments, contributing to color fastness and specific spectral properties.
• UV Absorber & Stabilizer Production: A key precursor for compounds used to protect plastics, coatings, and cosmetics from ultraviolet light degradation.
• Peptide & Biochemical Research: Facilitates the acylation of amino groups or hydroxyl groups in complex molecule construction for biochemical studies.

Basic Information

Product Name	Benzeneacetyl Chloride, 4-Hydroxy-
CAS No.	37859-23-7
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	4-Hydroxybenzoyl chloride; p-Hydroxybenzoyl chloride; 4-Hydroxybenzoic acid chloride; 4-Carboxyphenol chloride; p-Carboxyphenyl chloride; (4-Hydroxyphenyl)carbonyl chloride; 1-Chloro-1-oxo-4-hydroxybenzene
EINECS	Contact for details

Quality Control

Our Benzeneacetyl Chloride, 4-Hydroxy- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of fine chemical and pharmaceutical-grade intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.