Description

2'-Deoxy-5-Methoxyuridine is a modified nucleoside analog of deoxyuridine, featuring a methoxy group at the 5-position of the uracil base. This specific molecular modification is crucial for its role as a key intermediate and building block in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in nucleoside chemistry, antiviral studies, and the synthesis of novel therapeutic agents. Our supply ensures high purity and batch-to-batch consistency, which are essential for reliable experimental and production outcomes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate DNA/RNA metabolism and related biological pathways.
• Antiviral Agent Development: Acts as a precursor in the research and development of potential therapeutic agents targeting viral polymerases.
• Labelled Compound Synthesis: A starting material for the preparation of isotopically labelled (e.g., 13C, 15N, 3H) nucleosides for tracer studies and metabolic research.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside-based drugs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, chemical biology, and drug discovery.

Basic Information

Product Name	2'-Deoxy-5-Methoxyuridine
CAS No.	37805-95-1
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	5-Methoxy-2'-deoxyuridine; 5-Methoxythymidine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-methoxyuracil; 5-Methoxy-1-(2-deoxy-β-D-ribofuranosyl)uracil; 5-MethoxydUrd; 5-MeO-dU; 5-Methoxydeoxyuridine; 2'-Deoxy-5-methoxythymidine
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-5-Methoxyuridine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.