Description

5-Methoxy Cytidine is a modified nucleoside analog of cytidine, where a methoxy group replaces the hydroxyl group at the 5' position of the ribose sugar. This structural modification is critical for its role as a key intermediate in the synthesis of oligonucleotides and modified RNA molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, antiviral drug development, and epigenetics research. The compound's high purity is essential for ensuring the fidelity and efficacy of downstream synthetic and biological applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in solid-phase synthesis to incorporate modified bases into DNA/RNA strands for research and therapeutic applications (e.g., siRNA, antisense oligonucleotides).
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism and epigenetics.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Life Science Reagents: A component in the manufacture of specialized kits and reagents for molecular biology and diagnostics.

Basic Information

Product Name	5-Methoxy Cytidine
CAS No.	37805-90-6
Molecular Formula	C10H15N3O5
Molecular Weight	257.24 g/mol
Synonyms	5'-O-Methylcytidine; 5-Methoxycytidine; Cytidine, 5'-O-methyl-; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(methoxymethyl)oxolan-2-yl]-4-aminopyrimidin-2-one; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(methoxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Methoxy Cytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.