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2',3',5'-Tri-o-Benzoyl-5-Methoxyuridine CAS NO 37805-86-0


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CAS No.:37805-86-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2',3',5'-Tri-o-Benzoyl-5-Methoxyuridine is a key protected nucleoside derivative used as a sophisticated building block in organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates for the development of novel pharmaceuticals and oligonucleotides. It is primarily utilized by the life sciences sector, including pharmaceutical R&D, biotechnology, and fine chemical synthesis, for applications in antiviral and anticancer drug discovery.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of modified nucleoside analogs for antiviral and anticancer therapeutic agents.
  • Oligonucleotide Synthesis: Serves as a protected monomer for the solid-phase or solution-phase synthesis of modified DNA/RNA strands in research and diagnostics.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive molecules and prodrug development.
  • Bioconjugation & Labeling: Acts as a starting material for creating labeled nucleosides used in probes and tracking studies.
  • Academic & Industrial R&D: Employed in chemical biology and organic synthesis laboratories for developing new synthetic methodologies.

Basic Information

Product Name 2',3',5'-Tri-o-Benzoyl-5-Methoxyuridine
CAS No. 37805-86-0
Molecular Formula C32H26N2O9
Molecular Weight 582.56 g/mol
Synonyms 5-Methoxyuridine, 2',3',5'-tribenzoate; 2',3',5'-Tri-O-benzoyl-5-methoxyuridine; 5-Methoxy-2',3',5'-tri-O-benzoyluridine; 1-[(2R,3R,4R,5R)-3,4-Bis(benzoyloxy)-5-(benzoyloxymethyl)oxolan-2-yl]-5-methoxypyrimidine-2,4-dione; Tribenzoyl 5-methoxyuridine
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Quality Control

Our 2',3',5'-Tri-o-Benzoyl-5-Methoxyuridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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