Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, (1R,2R,4R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant value in advanced organic synthesis. Its rigid bicyclic framework and reactive acid chloride functionality make it an essential precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is critically needed by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Employed to introduce the norbornene moiety into specialty polymers, resins, and advanced materials to modify thermal and mechanical properties.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, (1R,2R,4R)-Rel- (9Ci)
CAS No.	37750-50-8
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	(1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; (1R,2R,4R)-(-)-5-Norbornene-2-carbonyl chloride; endo-(-)-5-Norbornene-2-carbonyl chloride; (1R,2R,4R)-rel-5-Norbornene-2-carbonyl chloride; (1R,2R,4R)-Norborn-5-ene-2-carbonyl chloride; Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, (1R,2R,4R)-rel-; endo-(-)-Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.