Description

[5-[(1-Amino-2-Formamidoethylidene)Amino]-3,4-Dihydroxyoxolan-2-Yl]Methyl Dihydrogen Phosphate is a sophisticated nucleotide derivative and a key intermediate in biochemical synthesis. This compound matters for its role in the development and production of nucleoside analogs, which are critical in pharmaceutical research and diagnostic applications. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and life science sectors for developing antiviral agents, anticancer drugs, and molecular probes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a precursor in the study of nucleotide metabolism and enzyme mechanisms.
• Diagnostic Reagent Synthesis: Employed in the manufacturing of labeled nucleotides for diagnostic kits and assays.
• Antiviral Drug Development: Serves as a key intermediate in the research and production of nucleotide reverse transcriptase inhibitors (NRTIs).
• Life Science Tools: Utilized in the preparation of modified nucleotides for next-generation sequencing and PCR applications.
• Academic & Industrial R&D: Fundamental material for exploring new chemical entities (NCEs) and novel biochemical pathways in both academic and corporate laboratories.

Basic Information

Product Name	[5-[(1-Amino-2-Formamidoethylidene)Amino]-3,4-Dihydroxyoxolan-2-Yl]Methyl Dihydrogen Phosphate
CAS No.	37721-04-3
Molecular Formula	C8H15N4O9P
Molecular Weight	342.20 g/mol
Synonyms	5'-O-Phosphonoformycin B; Formycin B 5'-Monophosphate; 5'-Phosphonoformycin B; 7-Amino-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine 5'-phosphate; Formycin B phosphate; 5'-Formycin B monophosphate; 5'-O-Phosphono-7-amino-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine; 7-Amino-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidin-5-ium-5-olate 5'-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Production follows strict protocols suitable for high-purity biochemical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We can support development projects requiring material that meets research-grade or higher specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.