Description

8-Chloroadenosine-5'-o-Monophosphate Sodium Salt is a chemically modified nucleotide monophosphate, specifically a chlorinated derivative of adenosine monophosphate (AMP). This modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex nucleotide analogs and pharmaceutical agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in enzymology studies, metabolic pathway research, and the development of novel therapeutic compounds.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for kinases, phosphatases, and other nucleotide-binding proteins.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of more complex nucleoside-based drugs and prodrugs.
• Metabolic Pathway Analysis: Employed in research to investigate adenosine-related signaling pathways and cellular energy metabolism.
• Molecular Biology: Can be used in the preparation of labeled nucleotides for tracing studies or diagnostic assays.
• Reference Standard: Acts as a high-purity analytical standard for quality control in pharmaceutical manufacturing and research.

Basic Information

Product Name	8-Chloroadenosine-5'-o-Monophosphate Sodium Salt
CAS No.	37676-40-7
Molecular Formula	C10H11ClN5NaO7P
Molecular Weight	409.64 g/mol
Synonyms	8-Chloro-AMP Sodium Salt; 8-Cl-AMP Na Salt; Sodium 8-chloroadenosine-5'-monophosphate; 8-Chloroadenosine 5'-(sodium phosphate); 8-Chloro-5'-AMP sodium salt; Adenosine, 8-chloro-, 5'-(dihydrogen phosphate), sodium salt (1:1); 8-Chloroadenosine 5'-monophosphate monosodium salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing specific results from HPLC, NMR, and other relevant analytical methods are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Conforms to ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.