Description

5-Amino-1-(2'-Deoxy-β-D-Ribofuranosyl)Imidazole-4-Carboxamide is a key nucleoside intermediate and precursor in the synthesis of purine nucleotides and their analogs. This compound matters for its critical role in biochemical research and the development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in nucleoside chemistry and nucleic acid synthesis.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of purine-based nucleoside analogs used in antiviral and anticancer drug discovery.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies, metabolic pathway analysis, and nucleotide biosynthesis research.
• Nucleic Acid Chemistry: Serves as a starting material for the preparation of modified nucleosides and oligonucleotides for diagnostic and therapeutic applications.
• Academic Research: Employed in university and institutional labs for studying enzyme mechanisms, such as those of purine biosynthetic enzymes.
• Process Development: Used in scaling up synthetic routes for novel nucleoside drugs, supporting process chemistry and optimization.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	5-Amino-1-(2'-Deoxy-β-D-Ribofuranosyl)Imidazole-4-Carboxamide
CAS No.	37642-56-1
Molecular Formula	C9H14N4O5
Molecular Weight	258.23 g/mol
Synonyms	5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; AICAR; Acadesine; 5-Amino-1-β-D-ribofuranosylimidazole-4-carboxamide; 5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; 5-Aminoimidazole-4-carboxamide ribonucleoside; 5-Amino-1-(β-D-ribofuranosyl)imidazole-4-carboxamide; AICA ribonucleoside
EINECS	Contact for details

Quality Control

Our 5-Amino-1-(2'-Deoxy-β-D-Ribofuranosyl)Imidazole-4-Carboxamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.