Description

1-Imidazolidinecarbonyl Chloride, 2-Thioxo- (9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in the presence of both a highly reactive acid chloride group and a thioxo moiety, enabling its use in the construction of complex molecular architectures. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Peptidomimetic Research: Serves as a precursor for introducing imidazolidine-thione motifs into peptide backbones to modulate stability and bioactivity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal coordination chemistry and catalysis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing specific chemical functionalities into polymer chains.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzymatic activity and biological pathways.

Basic Information

Product Name	1-Imidazolidinecarbonyl Chloride, 2-Thioxo- (9Ci)
CAS No.	37627-16-0
Molecular Formula	C4H5ClN2OS
Molecular Weight	148.61 g/mol
Synonyms	2-Thioxoimidazolidine-1-carbonyl chloride; 2-Thioxo-1-imidazolidinecarbonyl chloride; 1-Carbamoylimidazolidine-2-thione chloride; 2-Imidazolidinone, 1-(chlorocarbonyl)-, thio-; Imidazolidine-2-thione, 1-carbonyl chloride; 1-Imidazolidinecarbonyl chloride, 2-thioxo-
EINECS	Contact for details

Quality Control

Our 1-Imidazolidinecarbonyl Chloride, 2-Thioxo- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, strong oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.