Description

2-Chloro-Benzothiazole-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its dual functional groups, which make it a versatile building block for constructing complex heterocyclic systems. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel benzothiazole-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require the benzothiazole scaffold for bioactivity.
• Dye and Pigment Manufacturing: Serves as a precursor for developing specialized heterocyclic dyes and optical brighteners.
• Material Science Research: Employed in the creation of organic ligands for catalysis and in the development of advanced polymeric materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services targeting high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-Chloro-Benzothiazole-4-Carbonyl Chloride
CAS No.	37525-58-9
Molecular Formula	C8H3Cl2NOS
Molecular Weight	232.08 g/mol
Synonyms	2-Chloro-1,3-benzothiazole-4-carbonyl chloride; 2-Chlorobenzo[d]thiazole-4-carbonyl chloride; 4-(Chlorocarbonyl)-2-chlorobenzothiazole; 2-Chloro-4-chlorocarbonylbenzothiazole; Benzothiazole-4-carbonyl chloride, 2-chloro-; 37525-58-9 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-Benzothiazole-4-Carbonyl Chloride is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for sensitive synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.