Description

2,6-Dichloropurine-2'-Deoxyriboside is a key nucleoside analog intermediate of significant importance in pharmaceutical research and development. This compound is valued for its role as a versatile building block in the synthesis of modified nucleosides and potential antiviral or anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of novel therapeutic compounds and biochemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used in the study of enzyme mechanisms, nucleic acid metabolism, and as a precursor for labeled compounds.
• Prodrug Development: Serves as a key starting material for creating prodrugs designed for targeted drug delivery.
• Antisense Oligonucleotide Synthesis: Acts as a modified nucleoside precursor in the construction of oligonucleotides for genetic research and therapeutic applications.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore new chemical entities with potential biological activity.

Basic Information

Product Name	2,6-Dichloropurine-2'-Deoxyriboside
CAS No.	37390-66-2
Molecular Formula	C10H10Cl2N4O4
Molecular Weight	321.12 g/mol
Synonyms	2,6-Dichloro-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine; 2,6-Dichloropurine deoxyriboside; 2'-Deoxy-2,6-dichloropurine riboside; 9-(2-Deoxy-β-D-ribofuranosyl)-2,6-dichloropurine; 2,6-Dichloro-9H-purin-9-yl 2-deoxy-β-D-ribofuranoside; NSC 107429
EINECS	Contact for details

Quality Control

Our 2,6-Dichloropurine-2'-Deoxyriboside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.