Description

Sinistrin is a high-purity, naturally occurring polysaccharide derived from plants, known for its specific renal clearance properties. This compound is of critical importance in clinical diagnostics and pharmaceutical research, serving as a precise marker for measuring glomerular filtration rate (GFR). It is primarily utilized by pharmaceutical manufacturers, clinical diagnostic laboratories, and advanced research institutions developing renal function tests and related medical applications.

Application

• Renal Function Diagnostics: As the active pharmaceutical ingredient (API) in injectable solutions for the precise measurement of glomerular filtration rate (GFR).
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the calibration and validation of analytical methods in pharmacokinetic studies.
• Clinical Research: Employed in studies investigating kidney physiology, nephrotoxicity of new drug candidates, and the progression of renal diseases.
• Biochemical Reagent: Serves as a substrate or standard in enzymatic and chromatographic assays within life science research.
• Veterinary Medicine: Applied in renal function assessment for companion animals and livestock in veterinary clinical settings.

Basic Information

Product Name	Sinistrin
CAS No.	37311-25-4
Molecular Formula	C18H32O16 (monomer unit)
Molecular Weight	504.44 g/mol (monomer)
Synonyms	Polyfructosan-S; Inutest; (2->1)-Fructofuranan; Fructosan from *Cichorium intybus*; Chicory Inulin; Polyfructose; Beta(2-1)-Polyfructofuranosyl-α-D-Glucopyranoside; GFR-Marker
EINECS	Contact for details

Quality Control

Our Sinistrin is manufactured and tested under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical and diagnostic use. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and safety parameters. We can supply material compliant with relevant pharmacopeial standards (e.g., Ph. Eur., USP) for API use upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and analytical results.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	< 0.05 EU/mg (for injectable grade)
Microbial Enumeration	Meets Ph. Eur. criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.