Description

2-(Para-Nitrophenyl)-Adenosine is a chemically modified nucleoside derivative, where a para-nitrophenyl group is attached to the adenosine moiety. This modification is crucial for its role as a key intermediate and biochemical tool in pharmaceutical research and diagnostic development. It is primarily sought by researchers and manufacturers in the life sciences sector for its utility in enzyme assays, nucleotide analog synthesis, and as a probe for studying adenosine receptor interactions.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic studies, particularly for kinases and other ATP-utilizing enzymes.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel nucleoside-based drug candidates and prodrugs.
• Diagnostic Reagent Development: Employed in the formulation of assay kits for detecting specific enzymatic activities or for cellular signaling studies.
• Probe Synthesis: Acts as a precursor for labeled (e.g., fluorescent, radioactive) adenosine analogs used in molecular biology and receptor binding assays.
• Academic & Industrial R&D: Utilized in universities and corporate R&D labs for fundamental research into nucleotide metabolism and signaling pathways.

Basic Information

Product Name	2-(Para-Nitrophenyl)-Adenosine
CAS No.	37151-16-9
Molecular Formula	C17H18N8O6
Molecular Weight	430.37 g/mol
Synonyms	2-(p-Nitrophenyl)adenosine; 2-(4-Nitrophenyl)adenosine; Adenosine, 2-(4-nitrophenyl)-; N6-(4-Nitrobenzyl)adenosine (common misnomer); 2-(4-Nitrophenyl)-9-β-D-ribofuranosyl-9H-purin-6-amine; p-Nitrophenyladenosine
EINECS	Contact for details

Quality Control

Our 2-(Para-Nitrophenyl)-Adenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay value. Our quality commitment ensures material consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.