Description

3,4-Bis(Trimethylsilyloxy)Phenylacetic Acid Trimethylsilyl Ester is a key organosilicon-protected intermediate, primarily valued for its role in synthetic organic chemistry. Its core function is to protect reactive hydroxyl and carboxylic acid groups, enabling complex multi-step synthesis in sensitive environments. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a protected synthon in the multi-step synthesis of complex drug molecules, particularly those containing catechol or phenylacetic acid moieties.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where selective protection of functional groups is required.
• Peptide & Prodrug Chemistry: Facilitates the synthesis of peptide analogs and prodrugs by providing temporary protection for carboxylic acid groups under mild conditions.
• Material Science Research: Acts as a precursor or modifying agent in the development of specialty silicones and silicon-containing polymers.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	3,4-Bis(Trimethylsilyloxy)Phenylacetic Acid Trimethylsilyl Ester
CAS No.	37148-62-2
Molecular Formula	C17H32O4Si3
Molecular Weight	384.69 g/mol
Synonyms	Phenylacetic acid, 3,4-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester; 3,4-Bis-O-(trimethylsilyl)phenylacetic acid TMS ester; TMS-protected 3,4-dihydroxyphenylacetic acid; 3,4-Di-O-trimethylsilyl-DOPAC TMS ester; Trimethylsilyl 2-(3,4-bis(trimethylsilyloxy)phenyl)acetate; DOPAC tris(trimethylsilyl) ether; 37148-62-2; Tris(trimethylsilyl) 3,4-dihydroxyphenylacetate
EINECS	Contact for details

Quality Control

Our 3,4-Bis(Trimethylsilyloxy)Phenylacetic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions, such as in a glovebox or under a nitrogen atmosphere, to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.