Description

8-Bromo-n-Methyl-Adenosine is a chemically modified nucleoside derivative, serving as a crucial building block and intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile precursor for the development of novel pharmaceutical compounds, particularly in antiviral and anticancer research. This high-purity intermediate is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel adenosine receptor agonists/antagonists and other therapeutic nucleoside analogs.
• Antiviral Research: Used in the development of potential antiviral agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating investigational anti-cancer prodrugs and targeted therapies.
• Biochemical Tool Compound: Utilized in enzymatic studies and as a substrate analog to investigate adenosine-related metabolic pathways.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by introducing bromine and methyl modifications to the adenosine scaffold.
• Fine Chemical Synthesis: Intermediate for the production of more complex, labeled, or functionalized nucleoside derivatives.

Basic Information

Product Name	8-Bromo-n-Methyl-Adenosine
CAS No.	37116-71-5
Molecular Formula	C11H14BrN5O4
Molecular Weight	360.17 g/mol
Synonyms	8-Bromo-N-methyladenosine; 8-Bromoadenosine, N-methyl-; 8-Br-N-Me-Ado; N-Methyl-8-bromoadenosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-bromo-6-(methylamino)purine; 8-Bromo-N6-methyladenosine; Adenosine, 8-bromo-N-methyl-
EINECS	Contact for details

Quality Control

Our 8-Bromo-n-Methyl-Adenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.