Description

N6-Benzyl-2-Deoxyadenosine is a chemically modified nucleoside derivative, specifically an N6-benzylated analog of 2'-deoxyadenosine. This compound is a valuable synthetic intermediate and research tool in medicinal chemistry and biochemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutics and as a key building block in oligonucleotide synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel nucleoside-based drug candidates, including potential antivirals and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the function of adenosine deaminases, kinases, and other nucleoside-processing enzymes.
• Oligonucleotide Synthesis: Acts as a modified phosphoramidite precursor for the solid-phase synthesis of oligonucleotides with tailored properties for diagnostic and therapeutic applications.
• Chemical Biology Probes: Employed in the development of activity-based probes and affinity labels to study protein-nucleic acid interactions and cellular signaling pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	N6-Benzyl-2-Deoxyadenosine
CAS No.	37113-47-6
Molecular Formula	C₁₇H₁₉N₅O₃
Molecular Weight	341.36 g/mol
Synonyms	N6-Benzyladenine 2'-Deoxyriboside; 2'-Deoxy-N6-benzyladenosine; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-N6-benzyladenine; N6-Benzyl-9-(2-deoxy-β-D-ribofuranosyl)adenine; N6-Bn-dA; Bn-dA; N6-Benzyl-2'-deoxyadenosine
EINECS	Contact for details

Quality Control

Our N6-Benzyl-2-Deoxyadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.