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9-(2-Deoxy-β-D-Erythro-Pentofuranosyl)-6-(Methylthio)-9H-Purin-2-Amine CAS NO 37113-42-1
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CAS No.:37113-42-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9-(2-Deoxy-β-D-Erythro-Pentofuranosyl)-6-(Methylthio)-9H-Purin-2-Amine is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate for the synthesis of modified oligonucleotides and potential therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleic acid chemistry, antiviral drug discovery, and molecular biology.
Application
- Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel nucleoside-based antiviral or anticancer drug candidates.
- Oligonucleotide Synthesis: Building block for the solid-phase or solution-phase synthesis of modified DNA or RNA strands for research and diagnostic applications.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and related biological pathways.
- Proteomics & Genomics: Potential use in the development of probes, primers, or tools for genetic analysis and molecular diagnostics.
- Antiviral Agent Development: Research into its potential direct biological activity or as a precursor for compounds targeting viral polymerases.
- Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
Basic Information
| Product Name | 9-(2-Deoxy-β-D-Erythro-Pentofuranosyl)-6-(Methylthio)-9H-Purin-2-Amine |
| CAS No. | 37113-42-1 |
| Molecular Formula | C11H15N5O3S |
| Molecular Weight | 297.33 g/mol |
| Synonyms | 6-(Methylthio)-2-aminopurine 2'-deoxyriboside; 2-Amino-6-(methylthio)-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine; 2'-Deoxy-6-methylthiopurine riboside; 6-Methylmercaptopurine deoxyriboside; d6MMPr; 2-Amino-6-methylthio-9-(2-deoxy-β-D-ribofuranosyl)purine; 9H-Purin-2-amine, 9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-(methylthio)- |
| EINECS | Contact for details |
Quality Control
Our 9-(2-Deoxy-β-D-Erythro-Pentofuranosyl)-6-(Methylthio)-9H-Purin-2-Amine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch. We support compliance with cGMP guidelines for advanced pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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