Description

6-o-Methyl-2'-Doxyinosine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound matters for its role in the synthesis of novel therapeutic agents, particularly in antiviral and anticancer drug discovery programs. It is primarily needed by research institutions, pharmaceutical companies, and CDMOs (Contract Development and Manufacturing Organizations) engaged in the development of nucleotide-based therapeutics and molecular probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of modified oligonucleotides and nucleotide analogs for therapeutic applications.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Serves as a building block for creating nucleoside-based chemotherapeutic agents and targeted cancer therapies.
• Biochemical Research: Employed in studying enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Probe Synthesis: Utilized for creating labeled nucleotides for diagnostic assays and molecular biology techniques.
• Process Development: Used by CDMOs for scaling up synthetic routes for GMP (Good Manufacturing Practice) production of novel drugs.

Basic Information

Product Name	6-o-Methyl-2'-Doxyinosine
CAS No.	37109-88-9
Molecular Formula	C11H14N4O4
Molecular Weight	266.25 g/mol
Synonyms	6-O-Methyl-2'-deoxyinosine; 2'-Deoxy-6-O-methylinosine; 6-Methoxy-2'-deoxyinosine; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methoxy-3H-purin-2-one; 6-Methoxy-9-(2-deoxy-β-D-erythro-pentofuranosyl)purin-2(3H)-one; 2'-Deoxy-6-methoxy-9H-purin-6-ol; 6-Methoxy-2'-deoxy-9H-purin-6-ol
EINECS	Contact for details

Quality Control

Our 6-o-Methyl-2'-Doxyinosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.