Description

2-Fluoro-5'-Deoxyadenosine is a fluorinated nucleoside analog, a key synthetic intermediate in medicinal chemistry and life science research. This modified nucleoside is valued for its role in probing enzyme mechanisms and as a building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the function of kinases, polymerases, and other nucleoside-processing enzymes.
• Proteomics & Molecular Biology: Serves as a tool compound for studying nucleic acid metabolism and cellular signaling pathways.
• Antisense & Oligonucleotide Synthesis: Can be incorporated into oligonucleotide sequences to modulate their stability, binding affinity, and biological activity.
• Diagnostic Reagent Development: Employed in the creation of probes and assays for diagnostic applications.
• Chemical Biology: Acts as a versatile scaffold for developing activity-based probes and other chemical tools.

Basic Information

Product Name	2-Fluoro-5'-Deoxyadenosine
CAS No.	37076-78-1
Molecular Formula	C10H12FN5O3
Molecular Weight	269.23 g/mol
Synonyms	2-Fluoro-2'-deoxyadenosine; 2-Fluoro-2'-deoxyadenosine (common misnomer); 2-F-dAdo; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-2-fluoroadenine; 2-Fluoroadenine deoxyriboside; 2-Fluorodeoxyadenosine; 2-Fluoro-9-(2-deoxy-β-D-ribofuranosyl)adenine; 2-Fluoro-2'-deoxyadenosine (isomeric reference)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5'-Deoxyadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.