Description

3-Hydroxy Mepivacaine is a key pharmaceutical intermediate and metabolite of the local anesthetic mepivacaine. This compound matters for its critical role in drug development, metabolism studies, and the synthesis of high-purity active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, analytical laboratories, and research institutions focused on anesthetic development and pharmacokinetic analysis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of mepivacaine and related anesthetic compounds.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Metabolite Studies: Essential for pharmacokinetic and drug metabolism research to understand the biotransformation pathways of mepivacaine.
• Impurity Standard: Serves as a known impurity standard for HPLC and other chromatographic assays to ensure API purity.
• Biochemical Research: Employed in studies investigating the mechanism of action and side-effect profiles of local anesthetics.
• Custom Synthesis: A starting material for the custom synthesis of novel derivatives for pharmacological evaluation.

Basic Information

Product Name	3-Hydroxy Mepivacaine
CAS No.	37055-90-6
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	3-Hydroxymepivacaine; 1-Methyl-2',6'-pipecoloxylidide-3'-ol; N-(2,6-Dimethylphenyl)-1-methyl-3-hydroxy-2-piperidinecarboxamide; Mepivacaine 3-Hydroxy Metabolite; Mepivacaine Hydroxy Metabolite; 3'-Hydroxy Mepivacaine; LAC-43 (3-Hydroxy metabolite)
EINECS	Contact for details

Quality Control

Our 3-Hydroxy Mepivacaine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.