Description

(4-Iodophenyl)Acetyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in introducing the (4-iodophenyl)acetyl moiety, a key structural motif for creating complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the iodine atom can facilitate further functionalization or act as a leaving group in coupling reactions.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as cross-coupling reactions (e.g., Suzuki, Heck).
• Polymer and Material Science: Employed to create functional monomers or as a modifying agent to incorporate aromatic iodinated units into polymers for specialized electronic or optical materials.
• Peptide Mimetics and Bioconjugation: Useful for acylating amino groups in the synthesis of peptide analogs or for creating bioconjugation linkers in probe and diagnostic agent development.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	(4-Iodophenyl)Acetyl Chloride
CAS No.	37051-38-0
Molecular Formula	C8H6ClIO
Molecular Weight	280.49 g/mol
Synonyms	p-Iodophenylacetyl chloride; 4-Iodobenzeneacetyl chloride; (4-Iodophenyl)acetic acid chloride; 2-(4-Iodophenyl)acetyl chloride; 37051-38-0; 4-Iodophenacetyl chloride; (p-Iodophenyl)acetyl chloride
EINECS	Contact for details

Quality Control

Every batch of (4-Iodophenyl)Acetyl Chloride is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.